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Inflammatory myopathy is disease featuring weakness and inflammation of muscles and (in some types) muscle pain. The cause of much inflammatory myopathy is unknown (), and such cases are classified according to their symptoms and signs and electromyography, mri and laboratory findings. Dominant vastus lateralis (vl) muscle by needle biopsy using the bergstrom technique. The voluntaries were subjected to 7 days of oral dexamethasone (dex) (8mg once daily) administration. Dexamethasone was speciﬁcally selected, because steroid myopathy has been reported to be associated with the use of ﬂuorinated steroids [2,3]. Emg can also be useful in directing the site for a muscle biopsy in a patient with a myopathy. The emg examination has the advantage that multiple muscles and sites can be sampled easily and often can suggest a suitable muscle to biopsy. It is always desirable to biopsy an unequivocally abnormal muscle yet one that is not end stage. Steroid myopathies take two major forms: (1) an acute corticosteroid myopathy (acm), with rapid presentation of proximal and distal limb weakness, diaphragmatic weakness, and both type 1 and ii muscle fiber necrosis and (2) chronic steroid myopathy with insidious onset and late findings of proximal limb muscle weakness and atrophy [22, 23]. Steroid muscle-related involvement is a frequent but often underestimated adverse effect of steroid treatment. "if u took a muscle biopsy of someone w/ steroid myopathy what would you expect to see as opposed to a normal person?" answered by dr. Gregory zych: many changes seen: many changes may be seen; there may be increased sc. A muscle disorder includes patterns of weakness, loss of muscle tissue, electromyogram (emg) findings, or biopsy results that suggest a muscle problem. The muscle disorder can be inherited, such as muscular dystrophy, or acquired, such as alcoholic or steroid myopathy. The medical name for muscle disorder is myopathy. A muscle disorder includes patterns of weakness, loss of muscle tissue, electromyogram (emg) findings, or biopsy results that suggest a muscle problem. The muscle disorder can be inherited, such as muscular dystrophy, or acquired, such as alcoholic or steroid myopathy. The medical name for muscle disorder is myopathy. Necrotizing myopathy refers to a muscle disorder that involves necrosis or muscle cell death as seen on the muscle biopsy. The necrosis can be caused by a variety of reasons and may include toxic myopathies, drug-induced myopathies, muscular dystrophies, thyroid disease, etc. Mri can be used to select pathological muscle site in difficult cases avoid: muscles that were site of emg, injections,or trauma biopsy procedures. Technique: we almost always use open biopsy procedure to obtain muscle. Open biopsy strongly indicated for disorders with patchy pathology, e. Polymyositis do not use cautery, sutures, or clamps. Objective: to describe the clinical course and steroid responsiveness of a patient with subacute proximal symmetric weakness, very high serum creatine kinase activity, and myopathic pattern with fibrillations in the electromyogram, whose muscle biopsy showed necrotizing myopathy, with practically no inflammation. In these patients muscle biopsy reveals a classical vacuolar microtubular myopathic pattern without necrosis or inflammation. A lysosomal vacuolar myopathy with vacuoles containing myeloid bodies may also be detected in patients chronically treated with chloroquine and, to a lesser extent, with hydroxychloroquine
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The prefix 19-nor means that there is no methyl group in the 19th position in the testosterone molecule. Hence, the other, also very common, the name of nandrolone is 19-nortestosterone. Most common are the administrations of 50 mg/ml and 100 mg/ml. Deca durabolin is the most widespread and most commonly used injectable steroid. Its popularity is due to the simple fact that it exhibits many very favorable properties. Structurally nandrolone is very similar to testosterone. Deca durabolin is a favorite to thousands of steroid users. Norma deca durabolin is an injectable form of nandrolone decanoate. Release form – 2 ml vials, in 1 ml contains 100 mg of the active substance. The decanoate ester dissolves in the body very slowly, up to four weeks, although it reaches its maximum concentration in the blood after 1 – 2 weeks. Deca-durabolin is a well-known anabolic steroid made from the steroidal hormone nandrolone and can be hooked on the massive decanoate. 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